MAGNIMS Workshop
Bridging neuropathology and imaging: advancing postmortem MRI research in Multiple Sclerosis
RC2NB at Basel University Hospital
November 28th 2025
09.00 – 09.10: Welcome and introduction to the Workshop
Cristina Granziera & Gabriele de Luca
Session 1 – 09:10 – 09:50
MS Neuropathology – Key concepts – Foundational principles in postmortem imaging
Chairs: Ludwig Kappos & Frederik Barkhof
Key anatomic sites and key questions – What do we need to assess?
Gabriele de Luca (Oxford)
SLIDES
Key challenges and opportunities
Cristina Granziera (Basel)
SLIDES
Session 2 – 09:50 – 10:20
Cortical pathology and postmortem MRI
Chairs: Olga Ciccarelli & Menno Schoonheim
Surface-in paradigm
Tobias Granberg (Stockholm)
SLIDES
Inside-out paradigm
Maria Gaitán (NIH)
SLIDES
Discussion
Session 3 – 10:25 – 10:55
WM pathology and postmortem MRI
Chairs: Debora Pareto & Mara Rocca
Chronic inflammation
Assunta Dal Bianco (Vienna)
SLIDES
Remyelination
Riccardo Galbusera (Basel)
SLIDES
Discussion
Break – 11:00 – 11:15
Session 4 – 11:15 – 11:45
Spinal cord and postmortem MRI
Chairs: Jaume Sastre-Garriga & Massimo Filippi
Spinal cord pathology
Marco Pisa (Oxford)
SLIDES
Combined ultra-high-resolution postmortem MRI and histology
Charidimos Tsagkas (NIH / Basel)
SLIDES
Discussion
Session 5 – 11:50 – 12:30
Lymphatic system and Choroid Plexus
Chairs: Nicola de Stefano & Ahmed Toosy
Choroid plexus: bystander or active trigger of CNS pathology in MS?
Alessandro Cagol (Basel)
SLIDES
Brain Lymphatic System: With the flow
Paolo Preziosa (Milano)
SLIDES
Brain Lymphatic System: Against the flow
Britta Engelhart (Bern)
SLIDES
Moderated debate
Keynote lecture – 12:35 – 13:05
Multi-omics integration with postmortem MRI
Roberta Magliozzi (Verona)
SLIDES
Discussion
Closing remarks – 13.05 – 13:15
Mara Rocca & Jaume Sastre-Garriga
